A biphasic multiscale study of the mechanical microenvironment of chondrocytes within articular cartilage under unconfined compression
نویسندگان
چکیده
منابع مشابه
Unconfined compression of articular cartilage: nonlinear behavior and comparison with a fibril-reinforced biphasic model.
Mechanical behavior of articular cartilage was characterized in unconfined compression to delineate regimes of linear and nonlinear behavior, to investigate the ability of a fibril-reinforced biphasic model to describe measurements, and to test the prediction of biphasic and poroelastic models that tissue dimensions alter tissue stiffness through a specific scaling law for time and frequency. D...
متن کاملA cross-validation of the biphasic poroviscoelastic model of articular cartilage in unconfined compression, indentation, and confined compression.
The biphasic poroviscoelastic (BPVE) model was curve fit to the simultaneous relaxation of reaction force and lateral displacement exhibited by articular cartilage in unconfined compression (n=18). Model predictions were also made for the relaxation observed in reaction force during indentation with a porous plane-ended metal indenter (n=4), indentation with a nonporous plane ended metal indent...
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پژوهش حاضر ارائه ی توصیفی است از نظام آوایی گویش لری شهر اندیمشک، واقع در شمال غربی استان خوزستان. چهارچوب نظری این پژوهش، انگاره ی پسازایشی جزءمستقل می باشد. این پایان نامه شامل موارد زیر است: -توصیف آواهای این گویش به صورت آواشناسی سنتی و در قالب مختصه های زایشی ممیز، همراه با آوانوشته ی تفصیلی؛ -توصیف نظام آوایی گویش لری و قواعد واجی آن در چهارچوب انگاره ی پسازایشی جزءمستقل و معرفی برهم کن...
Depth-dependent Relaxation of Articular Cartilage in Unconfined Compression
INTRODUCTION Articular cartilage (AC) is an inhomogeneous, anisotropic and multiphasic composite. Depth-dependent strain distribution in full thickness AC has previously been investigated with optical methods (Guilak, 1995; Schinagl, 1997; Wang, 2003). Depth and time-dependent compressive strain has been predicted with theoretical models (Li, 2000; Wang, 2001). Most recently, Electronic Speckle...
متن کاملStrain-rate dependent stiffness of articular cartilage in unconfined compression.
The stiffness of articular cartilage is a nonlinear function of the strain amplitude and strain rate as well as the loading history, as a consequence of the flow of interstitial water and the stiffening of the collagen fibril network. This paper presents a full investigation of the interplay between the fluid kinetics and fibril stiffening of unconfined cartilage disks by analyzing over 200 cas...
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ژورنال
عنوان ژورنال: Journal of Biomechanics
سال: 2014
ISSN: 0021-9290
DOI: 10.1016/j.jbiomech.2014.05.001